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Tamil Nadu State Board · Microbiology

TAMIL NADU STATE BOARD CLASS 12 MICROBIOLOGY 2025

2025 · 38 questions · First 10 Solutions Free
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Q1 mcq 1 mark
Size of the Nano particles varies from __________.
a.
100 nm or more
b.
Less than 10 nm
c.
10 nm or more
d.
100 nm or less Correct Answer
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Nano particles are usually defined as particles with size of 100 nm or less, so the correct answer is (d) 100 nm or less. Options (a) and (c) are too large for the nano range, and (b) is too small and does not represent the full nano-scale range.
Q2 mcq 1 mark
Which among the following helps us in getting a 3-D picture of specimen ?
a.
Compound microscope
b.
TEM
c.
Simple microscope
d.
SEM Correct Answer
Step-by-Step AI Explanation
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Scanning Electron Microscope (SEM) helps us obtain a 3-D picture of the specimen, so the correct answer is (d) SEM. A compound microscope and a simple microscope give only a 2-D view, while TEM provides internal details of thin specimens but not a 3-D surface image.
Q3 mcq 1 mark
Which of the following agents are used as a preservative in Ophthalmic Solution ?
a.
Phenol
b.
Alcohol
c.
Aldehydes
d.
Quaternary ammonium salts Correct Answer
Step-by-Step AI Explanation
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Quaternary ammonium salts are used as preservatives in ophthalmic solutions, so the correct answer is (d). Phenol, alcohol, and aldehydes are used mainly as disinfectants or preservatives in other preparations, not typically for ophthalmic solutions.
Q4 mcq 1 mark
__________ is used in lake and swimming pools to retard the growth of algae.
a.
Formaldehyde
b.
Copper sulphate Correct Answer
c.
Alcohol
d.
Silver nitrate
Step-by-Step AI Explanation
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Copper sulphate is used in lakes and swimming pools to retard the growth of algae, so the correct answer is (b). Formaldehyde is a disinfectant, alcohol is used as an antiseptic/disinfectant, and silver nitrate is used for specific antimicrobial purposes, not for controlling algae in water bodies.
Q5 mcq 1 mark
For every one molecule of sugar glucose which is oxidized __________ molecule of pyruvic acid are produced.
a.
3
b.
1
c.
4
d.
2 Correct Answer
Step-by-Step AI Explanation
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One molecule of glucose, when oxidized in glycolysis, produces 2 molecules of pyruvic acid, so the correct answer is (d) 2. The other options are incorrect because glucose does not yield 1, 3, or 4 pyruvate molecules in this process.
Q6 mcq 1 mark
The micro-organisms grow best at pH value around :
a.
3.4
b.
4.0
c.
9.2
d.
7.0 Correct Answer
Step-by-Step AI Explanation
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Micro-organisms generally grow best at neutral pH, around 7.0, so the correct answer is (d). A pH of 3.4 or 4.0 is too acidic for most microbes, and 9.2 is too alkaline for their optimum growth.
Q7 mcq 1 mark
__________ is an example for primary screening.
a.
Auxanography Correct Answer
b.
Photography
c.
Telegraphy
d.
Cinematography
Step-by-Step AI Explanation
Verified Method
Auxanography is an example of primary screening, so the correct answer is (a). It is used to detect microorganisms that produce a particular nutrient or growth factor. The other options—photography, telegraphy, and cinematography—are unrelated to microbial screening.
Q8 mcq 1 mark
Weil's disease is caused by which of the following bacteria ?
a.
Leptospira interrogans Correct Answer
b.
Salmonella typhi
c.
Vibrio cholerae
d.
Escherichia coli
Step-by-Step AI Explanation
Verified Method
Weil's disease is caused by Leptospira interrogans, so the correct answer is (a). Salmonella typhi causes typhoid, Vibrio cholerae causes cholera, and Escherichia coli is associated with various intestinal and urinary infections.
Q9 mcq 1 mark
__________ is the causative agent of Syphilis.
a.
Treponema pallidum Correct Answer
b.
Neisseria meningitidis
c.
Staphylococcus aureus
d.
Streptococcus pyogenes
Step-by-Step AI Explanation
Verified Method
Syphilis is caused by the bacterium Treponema pallidum, a spirochete. Neisseria meningitidis causes meningococcal infections, Staphylococcus aureus causes skin and other pyogenic infections, and Streptococcus pyogenes causes diseases such as scarlet fever and pharyngitis.
Q10 mcq 1 mark
This disease was first observed by Leeuwenhoek after he discovered parasitic organisms in his stool under the microscope.
a.
Malaria
b.
Chaga's disease
c.
Ascariasis
d.
Giardiasis Correct Answer
Step-by-Step AI Explanation
Verified Method
Giardiasis is the disease first observed by Leeuwenhoek when he examined his stool under the microscope and noticed parasitic organisms. It is caused by the protozoan Giardia lamblia. Malaria is caused by Plasmodium, Chaga's disease by Trypanosoma cruzi, and ascariasis by Ascaris lumbricoides.
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Q11 mcq 1 mark
Demonstration of __________ is called as Reynolds-Braude phenomenon.
a.
Germ tube
b.
Arthrospore
c.
Sporangiospore
d.
Chlamydospore
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Q12 mcq 1 mark
Beta propiolactone vaccine is given for __________.
a.
Rabies virus
b.
HIV
c.
Hepatitis virus
d.
Influenza virus
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Q13 mcq 1 mark
Which type of virus is transmitted by serum or blood transfusion ?
a.
Hepatitis B virus
b.
Hepatitis A virus
c.
Chikungunya virus
d.
Zika virus
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Q14 mcq 1 mark
Hay Fever is caused by __________.
a.
Perfumes
b.
Dust
c.
Pollen grains
d.
All of the above
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Q15 mcq 1 mark
DNA is transcribed into __________.
a.
sRNA
b.
mRNA
c.
huRNA
d.
tRNA
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Q16 short answer
Give the importance of Stem cells.
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Q17 short answer
List out the dyes used for fluorescence microscopy.
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Q18 short answer
Define Disinfectants
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Q19 short answer
What is food Spoilage ?
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Q20 short answer
What is Fermentor (Bioreactor) ?
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Q21 short answer
Write the morphology of Clostridium tetani.
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Q22 short answer
Define Mycology.
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Q23 short answer
What is Transplantation ?
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Q24 short answer
What is Catabolism ?
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Q25 short answer
What are the applications of electron microscope ?
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Q26 short answer
What are the factors influencing the antimicrobial activity of chemical agents ?
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Q27 short answer
What are the advantages and disadvantages of food preservation ?
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Q28 short answer
Write any three attributes of improved strains.
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Q29 short answer
List out the four important species of the genus Shigella.
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Q30 short answer
Write a short note on Ringworm infection.
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Q31 short answer
With a neat diagram describe the trophozoite of Giardia.
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Q32 short answer
Write short notes on ELISA.
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Q33 short answer
Draw a flowchart of mode of action of antibiotics.
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Q34 long answer
Describe Tricarboxylic Acid Cycle. OR Explain the Kirby-Bauer Test.
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Q35 long answer
Write the differences between Light microscope and Electron microscope. OR List any five methods of preservation of micro-organisms.
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Q36 long answer
Explain about Methylene Blue dye Reduction Test (MBRT). OR Describe the life-cycle of large roundworm which grows to a length upto 40 cm that infects humans.
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Q37 long answer
Write the differences between Bactericidal and Bacteriostatic. OR Explain the pathogenesis of Vibrio cholerae.
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Q38 long answer
Explain Immediate Hypersensitivity Type-I. OR Explain in detail about Hepatitis A virus.
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