← Class 12 Board Exam (HSC)
Tamil Nadu State Board · Microbiology

TAMIL NADU STATE BOARD CLASS 12 MICROBIOLOGY 2024

2024 · 43 questions · First 10 Solutions Free
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Q1 mcq 1 mark
Who invented Phase Contrast microscope ?
a.
George Strokes
b.
Robert Koch
c.
Alexander Fleming
d.
Frits Zernike Correct Answer
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Frits Zernike invented the Phase Contrast microscope in the 1930s, for which he received the Nobel Prize in Physics in 1953. George Stokes is known for fluorescence, Robert Koch for the germ theory of disease, and Alexander Fleming for the discovery of penicillin.
Q2 mcq 1 mark
The number of ATP molecules generated from one molecule of glucose oxidiz ed in prokaryotes __________.
a.
34
b.
38 Correct Answer
c.
30
d.
36
Step-by-Step AI Explanation
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In prokaryotes, aerobic respiration of one glucose molecule yields a theoretical maximum of 38 ATP molecules. This occurs because, unlike in eukaryotes, there is no transport cost for moving NADH produced in glycolysis into the mitochondria, allowing for a higher net yield.
Q3 mcq 1 mark
First genetically produced animal by cloning technique is __________.
a.
Bally
b.
Shally
c.
Vally
d.
Dolly Correct Answer
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Dolly the sheep was the first mammal to be successfully cloned from an adult somatic cell using the technique of nuclear transfer in 1996.
Q4 mcq 1 mark
The minimum value of aw for the growth of the micro-organisms in foods should be around __________.
a.
0.78
b.
0.99
c.
0.50
d.
0.86 Correct Answer
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Water activity ($a_w$) is a measure of the available moisture for microbial growth. Most bacteria require an $a_w$ of at least 0.90, but the general minimum value for the growth of most common spoilage microorganisms in food is considered to be around 0.86.
Q5 mcq 1 mark
Which of the following chemical lack penetrating power ?
a.
Ethylene oxide
b.
Phenol Correct Answer
c.
Beta-propiolactone
d.
Iodine
Step-by-Step AI Explanation
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Phenols act by denaturing proteins and disrupting cell membranes; they possess poor penetrating power compared to gases like Ethylene oxide or Beta-propiolactone, which are used as gaseous sterilants due to their high penetrating capability.
Q6 mcq 1 mark
B.C.G. Vaccine gives immunity against which of the following disease ?
a.
Cholera
b.
Syphilis
c.
Diphtheria
d.
Tuberculosis Correct Answer
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B.C.G. (Bacillus Calmette-Guérin) vaccine is a vaccine primarily used against tuberculosis (TB). It is derived from an attenuated strain of Mycobacterium bovis.
Q7 mcq 1 mark
Which of the following statement is true concerning Entamoeba histolytica ?
a.
It is not transmitted through faecal-oral route.
b.
It has no cystic stage.
c.
Trophozoites live in large intestine of human. Correct Answer
d.
It is non-pathogenic.
Step-by-Step AI Explanation
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Entamoeba histolytica resides in the large intestine of humans in its trophozoite form, where it causes amoebic dysentery. Option (a) is false because it is transmitted via the faecal-oral route, (b) is false because it has a cystic stage, and (d) is false because it is pathogenic.
Q8 mcq 1 mark
Tinea Barbae is also called as __________.
a.
Barber’s itch Correct Answer
b.
Athlete’s foot
c.
Candidiasis
d.
Onchomycosis
Step-by-Step AI Explanation
Verified Method
Tinea barbae is a fungal infection of the bearded area of the face and neck, commonly referred to as 'Barber’s itch'. Athlete's foot is Tinea pedis, and Candidiasis is caused by Candida species.
Q9 mcq 1 mark
The precursor used in Penicillin production is __________.
a.
Hydrochloric acid
b.
Citric acid
c.
Phenyl acetic acid Correct Answer
d.
Tartaric acid
Step-by-Step AI Explanation
Verified Method
Phenyl acetic acid is the precursor used in the commercial production of Penicillin G to ensure that the side chain of the antibiotic molecule is specifically incorporated. Hydrochloric acid, Citric acid, and Tartaric acid are not used as precursors for Penicillin biosynthesis.
Q10 mcq 1 mark
Identify the mismatched pair from the following :
a.
Type III- Immune complex
b.
Type I - Atopy
c.
Type IV- Mantoux reaction
d.
Type II- Arthus reaction Correct Answer
Step-by-Step AI Explanation
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Type II hypersensitivity involves cytotoxic reactions (antibody-dependent), while Arthus reaction is an example of Type III hypersensitivity (immune complex-mediated). Therefore, (d) is the mismatched pair. Type I (Atopy), Type III (Immune complex), and Type IV (Mantoux/delayed type) are correctly matched.
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Q11 mcq 1 mark
__________ sequence terminates protein synthesis.
a.
UAG
b.
UGA
c.
UAA
d.
All of the above
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Q12 mcq 1 mark
__________ is an example for mosquito-borne and tick borne viruses.
a.
Chikungunya virus
b.
Dengue virus
c.
HIV virus
d.
Flavi virus
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Q13 mcq 1 mark
__________ is called yeast like fungi.
a.
Saccharomyces
b.
Candida
c.
Aspergillus
d.
Cryptococcus
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Q14 mcq 1 mark
Enteric fever is caused by __________.
a.
Tryponema pallidum
b.
Escherichia coli
c.
Salmonella typhi
d.
Vibrio cholerae
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Q15 mcq 1 mark
__________ is an example for the smallest virus.
a.
Rabies virus
b.
Pox virus
c.
HIV virus
d.
Parvo virus
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Q16 short answer
Define Antiseptic. Give an example.
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Q17 short answer
State the methods of DNA sequencing.
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Q18 short answer
What is called freeze drying ?
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Q19 short answer
Write the applications of fluorescent microscopy.
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Q20 short answer
Define - Negribodies.
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Q21 short answer
Draw the diagram of a promastigote form of Leishmania donovani and label the parts.
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Q22 short answer
What are the types of Vectors ?
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Q23 short answer
What is opportunistic mycosis ?
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Q24 short answer
Write the names of the toxins produced by the organism causing lock jaw disease.
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Q25 short answer
Tabulate the differences between upstream and downstream fermentation process.
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Q26 short answer
Mention the characteristics of an Ideal Vector.
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Q27 short answer
Write the uses of Curd.
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Q28 short answer
Write about the prophylaxis for Diphtheria.
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Q29 short answer
Write about Chikungunya virus.
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Q30 short answer
What is black water fever ?
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Q31 short answer
Write a short note on Germ Tube test.
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Q32 short answer
What is meant by MBC and MIC test ?
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Q33 short answer
Which is acting as a biocatalyst ? Mention its uses.
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Q34 long answer
Write the differences between SEM and TEM.
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Q34 long answer
Explain Glycolysis pathway.
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Q35 long answer
Explain the various phases of Penicillin production with diagram.
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Q35 long answer
Describe the methods of Food Preservation.
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Q36 long answer
Write in detail about the life cycle of Giardia lamblia.
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Q36 long answer
Explain the structure of Hepatitis B virus.
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Q37 long answer
Explain the Direct ELISA with diagram.
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Q37 long answer
Explain the stages involved in recombinant DNA technology.
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Q38 long answer
Explain the Phenol Coefficient test.
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Q38 long answer
Explain about the toxins produced by the bacteria having grape like cluster appearance.
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